Drug reduces brain damage, hemorrhaging in rodents afflicted by stroke

By Alison Trinidad

An experimental drug called 3K3A-APC appears to reduce brain damage, eliminate brain hemorrhaging and improve motor skills in older stroke-afflicted mice and stroke-afflicted rats with comorbid conditions such as hypertension, according to a new study from Keck Medicine of USC.

The study, which appears online in the journal Stroke, provides additional evidence that 3K3A-APC may be used as a therapy for stroke in humans, either alone or in combination with the FDA-approved clot-busting drug therapy tPA (tissue plasminogen activator). Clinical trials to test the drug’s efficacy in people experiencing acute ischemic stroke are expected to begin recruiting patients in the United States in 2014. … Read More »

November 11th, 2013|Announcements|

Open enrollment an opportunity to choose Keck Medicine physicians

Open enrollment for benefits-eligible faculty and staff of the University has begun, and personnel are encouraged to choose Keck Medicine of USC providers by signing up for the USC Network Medical Plan.  … Read More »

November 8th, 2013|Announcements|

Researchers at USC uncover new possibilities for sweat gland stem cells

By Marie Rippen

Sweat is important — without it, we would overheat and die. In a recent paper in the journal Public Library of Science One (PLOS ONE), USC faculty member Krzysztof Kobielak, MD, PhD, and a team of researchers explored the ultimate origin of this sticky, stinky but vital substance — sweat gland stem cells. … Read More »

November 8th, 2013|Announcements|

Keck students, benefactors celebrate success at Scholarship Luncheon

By Ryan Ball

Donor Norene Zapanta with Maria Sandoval, recipient of the scholarship named for Zapanta’s late husband, Edward Zapanta, a USC neurosurgeon and the first Hispanic member of the USC Board of Trustees. (Photo/Steve Cohn) Donor Norene Zapanta with Maria Sandoval, recipient of the scholarship named for Zapanta’s late husband, Edward Zapanta, a USC neurosurgeon and the first Hispanic member of the USC Board of Trustees.
(Photo/Steve Cohn)

The daughter of undocumented immigrants, Maria Sandoval credits excellent mentoring for helping her become the first member of her family to graduate high school and college. Now in her third year at the Keck School of Medicine of USC, she’s getting another boost in her quest to become a primary care physician and practice in her underserved community in the San Fernando Valley.

Sandoval is the recipient of this year’s scholarship named for Edward Zapanta, MD, the late USC neurosurgeon and first Hispanic member of the USC board of trustees. She recently had to the opportunity to thank Norene Zapanta for continuing her husband’s support of Hispanic medical students. The two shared a meal at the Keck School’s annual Scholarship Luncheon, held on Oct. 2 on the Harry and Celesta Pappas Quad. … Read More »

November 8th, 2013|Announcements|

Researchers identify gene variant that raises risk for colorectal cancer from eating processed/red meat

By Suzanne Wu

A common genetic variant that affects one in every three people significantly increases the risk of colorectal cancer from consuming red meat and processed meat, according to a study presented at the annual American Society of Human Genetics 2013 meeting, the largest gathering of human geneticists in the world.

In addition, the study — the first to identify the interactions of genes and diet on a genome-wide scale — also reveals another specific genetic variation that appears to modify whether eating more vegetables, fruits and fiber actually lowers your colorectal cancer risk. … Read More »

November 5th, 2013|Announcements|