Experimental drug reduces brain damage, eliminates brain hemorrhaging in rodents afflicted by stroke

By Alison Trinidad

An experimental drug called 3K3A-APC appears to reduce brain damage, eliminate brain hemorrhaging and improve motor skills in older stroke-afflicted mice and stroke-afflicted rats with comorbid conditions such as hypertension, according to a new study from Keck Medicine of USC.

The study, which appears online in the journal Stroke, provides additional evidence that 3K3A-APC may be used as a therapy for stroke in humans, either alone or in combination with the FDA-approved clot-busting drug therapy tPA (tissue plasminogen activator). Clinical trials to test the drug’s efficacy in people experiencing acute ischemic stroke are expected to begin recruiting patients in the United States in 2014. … Read More »

November 20th, 2013|Announcements|

USC STEM CELL SOCIAL

(Photo/Cristy Lytal) (Photo/Cristy Lytal)

The dessert tray and cheese platter seemed self-renewing at the first USC Stem Cell Social, held on Oct. 25 at the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC. Nearly 100 guests toured the labs, viewed research posters, voted on their favorite scientific images and mingled with researchers and faculty at this public event hosted by USC Stem Cell and the California Institute for Regenerative Medicine (CIRM) in honor of Stem Cell Awareness Day. … Read More »

November 20th, 2013|Announcements|

Tiny technology may be the future of medicine

By Robert Perkins

Sometimes the smallest tools are required to tackle the biggest problems. At the forefront of innovative research on regenerative medicine and cancer treatment, experts from the top research institutions in the greater Los Angeles area converged for the first-ever UCLA-USC-Caltech Nanotechnology and Nanomedicine Symposium on Oct. 18. … Read More »

November 20th, 2013|Announcements|

USC professor at CHLA awarded $9.5 million by NIH for sickle cell disease research

By Ellin Kavanagh

Thomas Coates, MD, professor of pediatrics and pathology at the Keck School of Medicine of USC and section head of hematology in the division of hematology oncology at Children’s Hospital Los Angeles, along with four other co-principal investigators, recently received a five-year, $9.5 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health. The award will fund research into the underlying physiology of sickle cell disease (SCD) and identification of biomarkers that will aid in the development of new treatment options. … Read More »

November 20th, 2013|Announcements|

Rare fetal cardiac procedure performed for the first time in Southern California by USC physicians at CHLA

By Lorenzo Benet

A mother and her 25-week-old fetus are doing well after a USC surgeon and pediatrician performed a successful in utero cardiac interventional procedure on the fetus at CHA Hollywood Presbyterian Medical Center late last month.

The minimally invasive procedure, known as a fetal aortic valvuloplasty, was a first for a Southern California hospital. Designed to treat a congenital heart defect known as critical aortic stenosis and evolving hypoplastic left heart syndrome, doctors succeeded in using a tiny balloon to open the fetus’s narrow aortic valve to increase blood flow to the body, improve left heart function and promote normal left heart growth during the critical third trimester growing stage. … Read More »

November 20th, 2013|Announcements|