USC Stem Cell scientists from the McMahon Lab have undertaken a pair of complementary studies, published in the journal Development, that provide new insight into the critical role of Wnt signaling in initiating the development of the mammalian kidney.

The Wnt pathway is a group of essential signaling molecules that emerged early in the evolution of multicellular life. Scientists have been studying Wnt actions for four decades to comprehend its complex roles in development and disease.

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