Ostrow study illustrates how growth factor defect causes tongue malformation

By Beth Newcomb

New findings about how cell signaling directs tongue development may have big clinical applications for healing tongue defects, according to an Ostrow School of Dentistry of USC study in the Journal of Biological Chemistry.

Yang Chai, DDS, PhD, principal investigator of “Non-canonical transforming growth factor beta (TGFb) signaling in cranial neural crest cells causes tongue muscle developmental defects” and director of the Center for Craniofacial Molecular Biology at the Ostrow School of Dentistry, said the tongue is a unique, highly mobile muscular organ that many view as a “fifth limb.” When the tongue develops improperly or is damaged by injury or disease, it cannot regenerate on its own.

“The current standard of care is to repair the tongue surgically using a skin flap, but it doesn’t have the muscle components to move the tongue and lacks the ability to taste food,” explained Chai. “We want to understand how the tongue is formed and how we can use that knowledge to regenerate the tongue.” … Read More »

December 23rd, 2013|Announcements|

High school students hit the lab for summer learning at Keck School

By Leslie Ridgeway

Jason Chen and Diana Zhou, both seniors at Diamond Bar High School, part of the Summer High School Advanced Research Program, work on a device they designed and built to measure reaction time. They envision using a form of the device in a future medical technology designed to warn surgeons of potential errors during procedures. (Photo/Jon Nalick) Jason Chen and Diana Zhou, both seniors at Diamond Bar High School, part of the Summer High School Advanced Research Program, work on a device they designed and built to measure reaction time. They envision using a form of the device in a future medical technology designed to warn surgeons of potential errors during procedures.
(Photo/Jon Nalick)

While many high school students were spending their summer working at coffee shops and restaurants or on their tans, a group of more than 20 students from private and public high schools throughout the Los Angeles area dug in to intensive science projects as part of a new program based at the Keck School of Medicine of USC.

The Summer High School Advanced Research Program (SHSARP) gave students eight weeks of hands-on experience in several labs, including ophthalmology, cell and neurobiology and preventive medicine at the Keck School, and at the USC School of Pharmacy, USC School of Dentistry, USC Dornsife College of Letters, Arts and Sciences, and the USC Viterbi School of Engineering. … Read More »

October 18th, 2013|Announcements|

Ajay Vyas promoted to deputy health-care compliance officer

By Tania Chatila

Ajay Vyas, JD, has been promoted to deputy health-care compliance officer, effective Sept. 3. In his new role, Vyas is responsible for the day-to-day management and oversight of the compliance programs for Keck Hospital of USC, USC Norris Cancer Hospital, USC Verdugo Hills Hospital and the Keck Medical Center of USC.

He is also the compliance plan provider for USC Care Medical Group, the Ostrow School of Dentistry of USC, USC Division of Occupational Science and Occupational Therapy, USC Division of Biokinesiology and Physical Therapy and the USC School of Pharmacy.  … Read More »

October 2nd, 2013|Announcements|

USC announces winners of inaugural Regenerative Medicine Initiative Awards

By Cristy Lytal

Three newly assembled research teams within USC Stem Cell, the regenerative medicine initiative at USC, will take steps that could lead to future stem-cell based therapies for certain forms of deafness, bone defects and pediatric leukemia.

The teams are the winners of USC’s Regenerative Medicine Initiative (RMI), a University-wide program kick-started by $1.2 million in funding from the office of Carmen A. Puliafito, MD, MBA, dean of the Keck School of Medicine of USC. Each RMI Award provides up to $200,000 per year for two years to multi-investigator research collaborations that harness the full potential of USC-affiliated faculty members. … Read More »

August 9th, 2013|Announcements|

What It Means to Be a Trojan

By Pamela J. Johnson

USC honored undergraduates, graduate students and teaching assistants — including four from the health sciences — for their volunteer work at the annual USC Community Service Awards Dinner, held April 16 at Town and Gown on the University Park Campus.

Health sciences honorees included Conan Teng of Ostrow School of Dentistry of USC; Jane Desmond and Kendra King Treichler of USC Occupational Science and Occupational Therapy; and Amanda Wong of the USC School of Pharmacy. … Read More »

June 24th, 2013|Announcements|