A new study led by USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) will explore structural alterations in the brains of people with bipolar disorder (BD), a chronic mental illness with one of the highest rates of attempted suicide — and for which no biological tools currently exist to guide diagnosis or treatment. The goal is to transform researchers’ understanding of the disease in the hopes of developing more effective treatments.

The NIH-funded project supports efforts by the Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium’s Bipolar Disorder Working Group (ENIGMA-BD). ENIGMA-BD has fostered successful global collaborations among more than 230 researchers since 2012, resulting in the most extensive studies of BD and the brain ever conducted.

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