The results of a multi-institutional clinical trial led by Keck Medicine of USC show that surgically removing abdominal lymph nodes impacted by seminoma can treat the illness as effectively as chemotherapy and radiation, which would mean fewer long-term side effects.

The findings were published in the Journal of Clinical Oncology.

Seminoma is a slow-growing form of testicular cancer that, if left untreated, typically spreads to lymph nodes behind the retroperitoneum (the abdomen’s inner lining). The current go-to treatment is chemotherapy and radiation, which are unfortunately associated with long-term side effects such as cardiovascular disease and secondary cancers. These treatments also adversely affect a patient’s quality of life.

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