The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study from the USC Stem Cell laboratory of Ksenia Gnedeva. The findings were published in the Proceedings of the National Academy of Sciences (PNAS).
Researchers focused on a group of interacting genes called the Hippo pathway, which serve as a signal to inhibit cell proliferation in the ear during embryonic development. In their experiments, the scientists demonstrated that the Hippo pathway also suppresses the regeneration of damaged sensory receptors in the ear and eye of adult mice.
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