Researchers at the Keck School of Medicine of USC have found a drug with the potential for curbing the painful hyperinflammation caused by osteoarthritis.
The findings, published in Science Translational Medicine, indicate that a drug compound, R805/CX-011, may modulate an important cell receptor in the body’s immune system, GP130, that signals when antibodies should attack a virus or infection. The studies — which tested the drug on mice and other animals — showed that the compound can disrupt over-activation of inflammation and manage pain and stiffness.
The drug’s positive effects give researchers hope for its potential in upcoming trials with humans.
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