PhD student’s research featured on journal cover

djs_blood_121_22_cover-sample1.inddZhengfei Lu, a PhD candidate in the lab of Michael Lieber, the Rita and Edward Polusky Professor in Basic Research at the Keck School of Medicine of USC, is the first author of a research study featured on the cover of the May 30 issue of Blood, the journal of the American Society of Hematology.  The paper is titled “BCL6 breaks occur at different AID sequence motifs in Ig–BCL6 and non-Ig–BCL6 rearrangements.”

According to Lu, “chromosomal rearrangements are common in human cancer.  By analyzing chromosomal break sequences collected from patients, we have discovered the fingerprints left by the process that caused the lymphoma. Read More »

July 12th, 2013|Announcements|

USC research IDs potential treatment for deadly, HIV-related blood cancer

By Alison Trinidad

Researchers at the USC Norris Comprehensive Cancer Center have discovered a promising new way to treat a rare and aggressive blood cancer most commonly found in people infected with HIV.

The USC team shows that a class of drugs called BET bromodomain inhibitors effectively targets primary effusion lymphoma (PEL), a type of cancer for which those drugs were not expected to be effective. Read More »

July 12th, 2013|Announcements|