Occupational therapy students help ramp up peer’s home modification project

By Jen Waters

Occupational therapy student Donna Ozawa runs a circular saw to construct a wheelchair ramp for a classmate. Photo/Photo/Courtesy Division of Occupational Science and Occupational Therapy Occupational therapy student Donna Ozawa runs a circular saw to construct a wheelchair ramp for a classmate.
Photo/Photo/Courtesy Division of Occupational Science and Occupational Therapy

To many, do-it-yourself renovation projects can be a costly headache waiting to happen. But for occupational therapy student Donna Ozawa, it’s a real passion.

Ozawa has two decades of experience in disciplines including sculpture, design and wheelchair engineering. She received an executive certificate in home modification from the USC Davis School of Gerontology in 2012, and has worked with several professional and volunteer organizations to adapt home spaces to better fit residents’ needs.

Now a student in USC’s occupational therapy master’s class of 2015, Ozawa is pursuing a career that will allow her to seamlessly combine her experiences and interests to help people lead healthier, happier lives in their residences.

The purpose of home modification projects — such as placing non-slip backing under floor rugs, installing grab bars for easy shower entry and exit, or retrofitting entire houses to be wheelchair accessible — is to make tasks easier, reduce in-home accidents and support independent living. Read More »

January 24th, 2014|Announcements|

Valter Longo seeks clues to a long and healthy life

By Cristy Lytal

Valter Longo Valter Longo

Valter Longo, PhD, is out to prove that gerontology is a young man’s game. The 46-year-old USC professor of gerontology and biological sciences has dedicated his career to slowing the implacable process of aging.

Growing up in Genoa, Italy, Longo spent countless hours emulating the guitar stylings of rock legends Jimi Hendrix and Mark Knopfler from Dire Straits. At age 16, he moved to Chicago to take jazz guitar lessons before heading to the University of North Texas to continue his studies.

During his second year of college as a music major, Longo was tapped to direct the marching band. As his music sensibilities were deeply rooted in rock, he refused, and the music department told him to find a different major. “Without hesitation, I said, ‘I want to learn about aging,’” he said.

After receiving his PhD in biochemistry at UCLA, Longo decided to take a molecular approach to aging, so he joined the UCLA labs of chemist Joan S. Valentine, PhD, and geneticist Edith B. Gralla, PhD. Read More »

January 24th, 2014|Announcements|

Keck Medicine of USC performs world’s 1st epilepsy treatment implant

By Alison Trinidad

On Dec. 18, 2013, Keck Medicine of USC became the world’s first medical center to surgically implant a responsive brain device newly approved by the U.S. Food and Drug Administration (FDA) to treat epilepsy, with the potential to help millions of people worldwide.

The device, manufactured by NeuroPace Inc., detects and then directly responds to abnormal brain activity to prevent seizures before they occur. In a three-hour surgery, USC faculty physicians implanted the device in a 28-year-old Lakewood, Calif., woman who was diagnosed with epilepsy in 2004.

Kathleen Rivas, an aspiring journalist who sought care from the university’s student health center in 2009 while earning her master’s degree elected to have the implant because medication had not fully controlled her seizures. Over the next few months, her doctors will program the device to detect specific brain activity indicative of a seizure’s onset. Read More »

January 14th, 2014|Announcements|

Keck Medicine announces new Center for Neurorestoration

By Alison Trinidad

Patients who suffer from uncontrolled epilepsy now have new treatment options at Keck Medicine of USC, thanks to the recent founding of the USC Center for Neurorestoration.

The center proposes to physically test innovative neural engineering and basic neuroscience to restore neurological circuitry and function within the human brain.

Christianne Heck, MD, MMM, associate professor of neurology at the Keck School of Medicine of USC, medical director of the USC Comprehensive Epilepsy Program, and Charles Liu, MD, PhD, professor of neurosurgery and neurology at the Keck School, surgical director of the USC Comprehensive Epilepsy Program, are co-directors of the new center. Heck and Liu worked extensively over the last three years to build USC’s Level 4 epilepsy program. Read More »

January 14th, 2014|Announcements|

USC and CHLA launch imaging lab for translational research

By Ellin Kavanagh and Cristy Lytal

With the launch of the Translational Biomedical Imaging Laboratory (TBIL), investigators at USC and The Saban Research Institute of Children’s Hospital Los Angeles moved medical science closer to a day when diseases can be detected before symptoms appear.

TBIL is a unique, interdisciplinary collaboration that combines dynamic equipment, including state-of-the-art microscopes for imaging living specimens and whole organs, with an intellectual infrastructure of optical physicists, computer scientists, translational researchers and clinicians. Read More »

January 14th, 2014|Announcements|

Air pollution and genetics combine to increase risk for autism

By Alison Trinidad

Exposure to air pollution appears to increase the risk for autism spectrum disorder (ASD) among people who carry a genetic disposition for the disorder, according to newly published research led by scientists at the Keck School of Medicine of USC.

“Our research shows that children with both the risk genotype and exposure to high air pollutant levels were at increased risk of autism spectrum disorder compared to those without the risk genotype and lower air pollution exposure,” said the study’s first author, Heather E. Volk, PhD, MPH, assistant professor of research in preventive medicine and pediatrics at the Keck School and principal investigator at The Saban Research Institute of Children’s Hospital Los Angeles. Read More »

January 14th, 2014|Announcements|

Thomas Buchanan named Mayo H. Soley Award winner

By Amy Hamaker

Thomas A. Buchanan, MD, received the Mayo H. Soley Award for his dedication to research in diabetes and endocrinology. Thomas A. Buchanan, MD, received the Mayo H. Soley Award Read More »

January 14th, 2014|Announcements|

Boxes of Medicine

Members of the Keck Medical Center of USC community demonstrated a generous holiday spirit as they donated food for needy families in east Los Angeles. The medical center partnered with Canning Hunger for its annual Boxes of Love event as the medical center’s first Thanksgiving food drive. Read More »

January 14th, 2014|Announcements|

AHA honors USC’s Demetriades for a lifetime of dedication

By Sara Reeve

Demetrios Demetriades, MD, PhD, professor of surgery and chief of the division of trauma & critical care at the Keck School of Medicine of USC’s Department of Surgery, was recently honored with the American Heart Association’s 2013 Lifetime Achievement Award in Trauma Resuscitation Science. The award, presented at the 11th annual Resuscitation Science Symposium in Dallas on Nov. 16, 2013, recognized Demetriades for his leadership, service and contributions to trauma resuscitation science. Read More »

January 14th, 2014|Announcements|

Offering career advice

DSC_2142 Photo/Graciela Medina

Neurosurgeon Frank Acosta, MD, associate professor of clinical medicine at the Keck School of Medicine of USC, recently shared images of spinal disorders or abnormalities with Latino middle and high school boys as part of a career and personal growth event. Read More »

January 14th, 2014|Announcements|

Etcetera

Kathleen Page, MD, chair of the Maternal-Child Health Section at the USC Diabetes and Obesity Research Institute and assistant professor of Medicine at the Keck School of Medicine of USC, recently received a prestigious Pathway to Stop Diabetes award from the American Diabetes Association. The Diabetes Research Accelerator award helps support exceptional early career researchers who intend to continue their careers in diabetes research. Read More »

January 14th, 2014|Announcements|

Stem cell image of the month: A good head start

This colorful series of mouse skulls reveals stem cells, labeled with the protein Gli1, in the sutures between the calvaria bones in the upper part of the cranium.Untitled-1

Read More »

January 14th, 2014|Announcements|

Keck School alumnus helps bring $1 million gift to Keck Medicine

By Amy E. Hamaker

The strength of a university can often be measured by the commitment of its alumni. Nowhere is that more apparent than at the Keck School of Medicine of USC, where alumnus Tony Alamo (’91), MD, recently helped bring a gift of $1 million to the school from a family friend.

At a lunch between Alamo, Keck School Dean Carmen A. Puliafito, MD, MBA, and Mike Ensign, retired chairman of the board of directors/CEO of Mandalay Resort Group, Alamo suggested a gift to benefit physicians, Keck Hospital of USC and Keck School students. Read More »

January 14th, 2014|Announcements|

Exploring the connection between Alzheimer’s disease and stroke

By Shelby Roberts

Alzheimer’s disease is the No. 6 cause of death in the United States, and stroke is the No. 4 cause.

Helena Chui, MD, chair, Department of Neurology, Raymond and Betty McCarron Chair in Neurology, and professor of neurology and gerontology at the Keck School of Medicine of USC, recently gave a presentation on Alzheimer’s disease and its relation to stroke on Nov. 6 as the sixth lecture in an ongoing Stroke Seminar Series at the Rio Hando Community Center in Downey, Calif. The event was hosted by the Roxanna Todd Hodges Stroke Foundation. Read More »

December 24th, 2013|Announcements|

Top Trojan scientists converge at Neuroscience 2013

By Robert Perkins

Several key faculty members from USC presented the latest pioneering research in neuroscience at the Society for Neuroscience’s annual meeting in San Diego in November.
More than 30,000 scientists and collaborators from 80 countries gathered for presentations by luminaries in the field, including USC’s Antonio Damasio, MD, PhD, Berislav Zlokovic, MD, PhD, and Dan Campbell, PhD. Read More »

December 23rd, 2013|Announcements|

BEST OF THE WURST

Students, faculty and staff on the Health Sciences Campus were treated to German music and a feast of bratwurst, sauerkraut, German potato salad, beer and pretzels to celebrate the coming of October — and the USC Good Neighbors Campaign. Read More »

December 23rd, 2013|Announcements|

OT symposium convenes scholars of sensory integration research

By Mike McNulty

National experts on the sensory issues tied to autism and other neurodevelopmental disorders exchanged their respective research at the 24th USC Occupational Science Symposium, which brought together dozens of leaders from across the country to assess the field and prioritize future research directions.

Hosted by the USC Division of Occupational Science and Occupational Therapy and its Sensory Integration, Engagement and Family Program, more than 350 researchers, clinicians and educators attended the Nov. 7 event, titled “Sensory Integration at the Crossroads: Diverse Perspectives in Occupational Therapy Research.” Read More »

December 23rd, 2013|Announcements|

USC researchers apply brainpower to understanding neural stem cell differentiation

By Cristy Lytal

How do humans and other mammals get so brainy? USC researcher Wange Lu, PhD, and his colleagues shed new light on this question in a paper published in Cell Reports on Oct. 24.

The researchers donned their thinking caps to explain how neural stem and progenitor cells differentiate into neurons and related cells called glia. Neurons transmit information through electrical and chemical signals; glia surround, support and protect neurons in the brain and throughout the nervous system. Glia do everything from holding neurons in place to supplying them with nutrients and oxygen, to protecting them from pathogens.

By studying early mouse embryo neural stem cells in a petri dish, Lu and his colleagues discovered that a protein called SMEK1 promotes the differentiation of neural stem and progenitor cells. At the same time, SMEK1 keeps these cells in check by suppressing their uncontrolled proliferation. Read More »

December 23rd, 2013|Announcements|

Keck School Faculty Council discusses admissions, GME, research funding

By Amy E. Hamaker

The Keck School of Medicine of USC Faculty Council met in a Town Hall meeting on Oct. 15 at the Edmondson Faculty Center on the Health Sciences Campus to discuss medical recruitment, trends and financing in graduate medical education, research trends at the Keck School and faculty recruitment. Read More »

December 23rd, 2013|Announcements|

Ostrow study illustrates how growth factor defect causes tongue malformation

By Beth Newcomb

New findings about how cell signaling directs tongue development may have big clinical applications for healing tongue defects, according to an Ostrow School of Dentistry of USC study in the Journal of Biological Chemistry.

Yang Chai, DDS, PhD, principal investigator of “Non-canonical transforming growth factor beta (TGFb) signaling in cranial neural crest cells causes tongue muscle developmental defects” and director of the Center for Craniofacial Molecular Biology at the Ostrow School of Dentistry, said the tongue is a unique, highly mobile muscular organ that many view as a “fifth limb.” When the tongue develops improperly or is damaged by injury or disease, it cannot regenerate on its own.

“The current standard of care is to repair the tongue surgically using a skin flap, but it doesn’t have the muscle components to move the tongue and lacks the ability to taste food,” explained Chai. “We want to understand how the tongue is formed and how we can use that knowledge to regenerate the tongue.” Read More »

December 23rd, 2013|Announcements|